Saratov State University, Institute of Nanostuctures and Biosystems
«Poster report»
OF THE REPORT:
Daria Solovyeva, Anton Chistyakov, Eugeni Lukashev, Konstantin Mochalov, Vladimir Oleinikov, Igor Nabiev
Bondareva Olga Sergeevna
Composite materials based on electrospun nanofibers of polycaprolactone, incorporating vaterite microcontainers witn photodynamic dye.
Design of new biomimetic scaffolds for tissue engineering and drug delivery is actual task of regenerative medicine at the present time. There is a problem of sustained release of drug from scaffold.
In this work we propose the method of modification electrospun scaffold by including spherical calcium carbonate microcontainers CaCO3 into fibers.
The SEM images of received samples are shown Fig.1.
It was found that the most intensive growth of the coating thickness is observed at the Si content about 0.1 wt.% and more than 0.3 wt.%.
Research has shown that with increasing Si content up to 0.1% instead of the dense phase layers (Fig. 2a) the loose and thick coatings are formed.
The compact layer of qualitative δ phase becomes thin and discontinuous. The outbursts of brittle ζ crystallites are observed (Fig. 2b).
When the Si content is 0.77% the morphology of ζ crystallites is changed from columnar to dendritic (Fig. 2c).
The results of the study allow to explain the reasons of the coatings poor quality on steels containing Si.