SECTION: Life Science
SCIENTIFIC ORGANIZATION:
National University of Science and Technology "MISIS"
REPORT FORM:
«Oral report»
AUTHOR(S)
OF THE REPORT:
Fedor Senatov, Aleksey Maksimkin, Sergey Kaloshkin, Natalya Anisimova, Aleksey Kopylov, Mihail Kiselevsky
SPEAKER:
Senatov Feder V.
REPORT TITLE:
Biocompatible UHMWPE-based materials perspective for bone and cartilage replacement
TALKING POINTS:

In recent years, there is a trend to increase the role of implant surgery. In particular, clinical situations often occur where major traumas, congenital malformations or diseases result in need for reconstruction of defects of cartilage and bone. In this work biocompatible polymer composites perspective for bone and cartilage replacement were studied.

UHMWPE-based composites for cartilage and bone reconstruction were developed. UHMWPE scaffolds for bone reconstruction have high ductility in compression and bending, porosity of 60 – 80 % vol. with pore size: 100 - 800 microns. Number of fusion defects was reduced in case of UHMWPE for cartilage replacement. Such UHMWPE structures have high impact strength, high wear-resistance (wear is reduced in 3 times) and low coefficient of friction (friction in water 0.06), biocompatibility, bioresistance.

References

1) F.S. Senatov, M.V. Gorshenkov, V.V. Tcherdyntsev, S.D. Kaloshkin, V.A. Sudarchikov. Fractographic analysis of composites based on ultra high molecular weight polyethylene // Composites Part B, 56 (2014) 869–875

2) Senatov F.S., Gorshenkov M.V., Kaloshkin S.D., Tcherdyntsev V.V., Anisimova N.Yu.,Kopylov A.N., Kiselevsky M.V. Biocompatible polymer composites based on ultrahigh molecular weight polyethylene perspective for cartilage defects replacement / Journal of Alloys and Compounds, 586 (2014) S544–S547

3) F.S. Senatov, A.A. Baranov, D.S. Muratov, M.V. Gorshenkov, S.D. Kaloshkin, V.V.Tcherdyntsev. Microstructure and properties of composite materials based on UHMWPE after mechanical activation // Journal of Alloys and Compounds 10.1016/j.jallcom.2013.12.175

4) A. V. Maksimkin, S. D. Kaloshkin, V. V. Tcherdyntsev, D.I. Chukov, A. A. Stepashkin. Technologies for Manufacturing Ultrahigh Molecular Weight Polyethylene-Based Porous Structures for Bone Implants/ Biomedical Engineering, Vol. 47, No. 2, July, 2013, pp. 73-77